13D Filings
SPRUCE BIOSCIENCES, INC.
SPRB
Amendment
Ownership

4.20%

Total Shares

1,759,521

Issuer CIK

1683553

CUSIP

85209E109

Event Date

Jan 6, 2025

Accepted

Jan 10, 2025, 11:05 AM

Reporting Persons (12)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
John P. McKearn, Ph.D.
Individual
4.20%1,759,52101,759,521
Jay Schmelter
Individual
4.20%1,759,52101,759,521
Niall O'Donnell, Ph.D.
Individual
2.40%1,000,61432,5001,000,614
RiverVest Venture Fund IV, L.P.
Partnership
2.40%1,000,61401,000,614
RiverVest Venture Partners IV, L.P.
Partnership
2.40%1,000,61401,000,614
RiverVest Venture Partners IV, LLC
Other
2.40%1,000,61401,000,614
Thomas C. Melzer
Individual
0.20%758,9070758,907
RiverVest Venture Fund III, L.P.
Partnership
0.20%720,6560720,656
RiverVest Venture Partners III, L.P.
Partnership
0.20%758,9070758,907
RiverVest Venture Partners III, LLC
Other
0.20%758,9070758,907
RiverVest Venture Partners III (Ohio), LLC
Other
0.10%38,251038,251
RiverVest Venture Fund III (Ohio), L.P.
Partnership
0.10%38,251038,251
Disclosure Items (7)

Security Title

Common Stock, par value $0.001 per share

Issuer Name

SPRUCE BIOSCIENCES, INC.

Filing Persons

No change.

Business Address

No change.

Principal Occupation

No change.

Convictions

No change.

Citizenship

No change.

No change.

No change.

Percentage of Class

The aggregate number and percentage of the shares of Common Stock outstanding beneficially owned by each Reporting Person set forth below and on the cover pages hereof are based on 41,302,599 shares of Common Stock outstanding as of November 8, 2024, as reported in the Issuer's Form 10-Q filed with the SEC on November 12, 2024.

Number of Shares

(i) sole power to vote or to direct the vote: See line 7 of cover sheets; (ii) shared power to vote or to direct the vote: See line 8 of cover sheets; (iii) sole power to dispose or to direct the disposition: See line 9 of cover sheets; (iv) shared power to dispose or to direct the disposition: See line 10 of cover sheets. By virtue of the relationships described herein, the Reporting Persons may be deemed to constitute a "group" for purposes of Section 13(d)(3) of the Act. The filing of this Statement shall not be construed as an admission that the Reporting Persons are a group, or have agreed to act as a group. Each Reporting Person expressly disclaims beneficial ownership of the securities reported herein, except to the extent such Reporting Person actually exercises voting or dispositive power with respect to such securities.

Transactions

Except as set forth herein, none of the Reporting Persons has effected any transactions in shares of the Issuer's Common Stock during the last 60 days.

Shareholders

No other person is known to have the right to receive or the power to direct the receipt of dividends from, or any proceeds from the sale of, the shares of Common Stock beneficially owned by any of the Reporting Persons.

Date of 5% Ownership

The Reporting Persons ceased to own more than five percent of the outstanding Common Stock on January 7, 2025.

No change.

Exhibit A: Joint Filing Agreement, dated October 23, 2020, by and among RiverVest Venture Fund III, L.P., RiverVest Venture Fund III (Ohio), L.P., RiverVest Venture Partners III (Ohio), LLC, RiverVest Venture Partners III, L.P., RiverVest Venture Partners III, LLC, RiverVest Venture Fund IV, L.P., RiverVest Venture Partners IV, L.P., RiverVest Venture Partners IV, LLC, John P. McKearn, Jay Schmelter, Thomas C. Melzer and Niall O'Donnell.

SPRUCE BIOSCIENCES, INC. — Schedule 13D | 13D Filings