13D Filings
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NuCana plc
NCNA
Amendment
Ownership

5.10%

Total Shares

4,987,975

Issuer CIK

1709626

CUSIP

67022C205

Event Date

Feb 13, 2025

Accepted

Feb 14, 2025, 04:32 PM

SEC EDGARView Original Filing
Reporting Persons (8)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Sofinnova Capital VI FCPR
Other
5.10%4,987,9754,987,9750
Sofinnova Partners SAS
Other
5.10%4,987,9754,987,9750
Antoine Papiernik
Individual
5.10%4,987,9754,987,9750
Henrijette Richter
Individual
5.10%4,987,9754,987,9750
Maina Bhaman
Individual
5.10%4,987,9754,987,9750
Graziano Seghezzi
Individual
5.10%4,987,9754,987,9750
Anta Gkelou
Individual
5.10%4,987,9754,987,9750
Karl Naegler
Individual
5.10%4,987,9754,987,9750
Disclosure Items (5)

Security Title

Ordinary Shares, nominal value GBP0.04 per share

Issuer Name

NuCana plc

Issuer Address

3 Lochside Way, Edinburgh, X0, EH12 9DT

None of the Reporting Persons has, during the last five years, been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree, or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or state securities laws or finding any violation with respect to such laws.

Item 4 of the Schedule 13D is hereby amended and supplemented as follows: All of the Ordinary Shares and ADSs that are held of record by the Reporting Persons as reported herein were acquired for investment purposes. The Reporting Persons retain the right to change their investment intent, from time to time to acquire additional ADSs or other securities of the Issuer, or to sell or otherwise dispose of all or part of the ADSs or other securities of the Issuer, if any, beneficially owned by them, in any manner permitted by law. The Reporting Persons may engage from time to time in ordinary course transactions with financial institutions with respect to the securities described herein. Except as set forth above, none of the Reporting Persons currently has any plans or proposals which would be related to or would result in any of the matters described in Items 4(a)-(j) of the Instructions to Schedule 13D. However, as part of the ongoing evaluation of investment and investment alternatives, the Reporting Persons may consider such matters and, subject to applicable law, may formulate a plan with respect to such matters, and, from time to time, may hold discussions with or make formal proposals to management or the board of directors of the Issuer or other third parties regarding such matters.

Percentage of Class

Item 5(a) of the Schedule 13D is hereby amended and supplemented as follows: See Rows 11 and 13 of the cover page for each of the Filing Persons, which is incorporated herein by reference. The filing of this Schedule 13D shall not be construed as an admission by Papiernik, Richter, Bhaman, Seghezzi, Gkelou and Naegler that such person is, for the purposes of Section 13(d) of the Securities Exchange Act of 1934, the beneficial owner of any securities covered by this Statement. This Amendment is being filed to reflect a decrease in the Reporting Persons' percentage ownership of the Issuer's Ordinary Shares, which resulted from an increase in the number of Ordinary Shares outstanding since the filing of Amendment No. 5 to Schedule 13D and is not due to any transactions in the Ordinary Shares or ADSs by the Reporting Persons. Percentage of class is calculated based on 98,630,000 ordinary shares outstanding as of September 30, 2024, as reported in Exhibit 99.1 in NuCana plc's Form 6-K filed with the SEC on November 25, 2024.

Number of Shares

Item 5(b) of the Schedule 13D is hereby amended and supplemented as follows: See the information contained on the cover pages of this Amendment, which is incorporated herein by reference.

Transactions

Item 5(c) of the Schedule 13D is hereby amended and supplemented as follows: There have been no reportable transactions with respect to the Ordinary Shares or ADSs of the Issuer within the last 60 days by the Reporting Persons.

EX 99.1 - Joint Filing Agreement, dated as of February 14, 2025.