13D Filings
Lyra Therapeutics, Inc.
LYRA
Amendment
Ownership

0.00%

Total Shares

0

Issuer CIK

1327273

CUSIP

55234L204

Event Date

Nov 20, 2025

Accepted

Nov 25, 2025, 04:24 PM

Reporting Persons (4)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Perceptive Advisors LLC
Investment Adviser
0.00%000
Joseph Edelman
Individual
0.00%000
Perceptive Life Sciences Master Fund, Ltd.
CO
0.00%000
Perceptive LS (A), LLC
CO
0.00%000
Disclosure Items (2)

Security Title

Common Stock, $0.001 par value

Issuer Name

Lyra Therapeutics, Inc.

Issuer Address

480 Arsenal Way, Watertown, MA, 02472

Percentage of Class

Items 5(a)-(c) of the Schedule 13D are amended and supplemented as follows: The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference.

Number of Shares

The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference.

Transactions

Except as set forth on Schedule A, no Reporting Person has effected any transaction in shares of Common Stock since the filing of Amendment No. 9 to the Schedule 13D, filed with the Securities and Exchange Commission on November 18, 2025.

Date of 5% Ownership

On November 21, 2025, the Reporting Persons ceased being holders of 5% or more of the outstanding shares of the Issuer's Common Stock.