13D Filings
Connect Biopharma Holdings Limited
CNTB
Amendment
Ownership

21.50%

Total Shares

12,000,000

Issuer CIK

1835268

CUSIP

G23549101

Event Date

Nov 23, 2025

Accepted

Nov 26, 2025, 04:30 PM

Reporting Persons (4)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Panacea Innovation Limited
CO
21.50%12,000,000012,000,000
Panacea Venture Healthcare Fund II, L.P.
Partnership
21.50%12,000,000012,000,000
Panacea Venture Healthcare Fund II GP Company, Ltd.
CO
21.50%12,000,000012,000,000
James Huang
Individual
21.50%12,000,000012,000,000
Disclosure Items (3)

Security Title

Ordinary Shares

Issuer Name

Connect Biopharma Holdings Limited

Issuer Address

3580 Carmel Mountain Road, San Diego, CA, 92130

Item 3 of the Schedule 13D is hereby amended and supplemented as follows: Since Amendment No. 3, Panacea Venture Healthcare Fund II, L.P. has purchased 50,000 Ordinary Shares in a series of open market transactions at a weighted average price of $1.4641 per Ordinary Share. Panacea Venture Healthcare Fund II, L.P. obtained the funds used to purchase the Ordinary Shares through capital contributions from its partners.

Percentage of Class

Item 5 of the Schedule 13D is hereby amended and restated in its entirety as follows: The information contained on the cover pages to this Schedule 13D is incorporated by reference into this Item 5. The ownership information presented herein represents beneficial ownership of Ordinary Shares as of the date of this filing, based upon 55,903,513 Ordinary Shares outstanding as of October 31, 2025, as disclosed in the Issuer's Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on November 12, 2025. Panacea Venture Healthcare Fund II, L.P. is the record holder of the Ordinary Shares reported herein. James Huang is the sole owner of Panacea Innovation Limited, which is the sole owner of Panacea Venture Healthcare Fund II GP Company, Ltd., which is the general partner of Panacea Venture Healthcare Fund II, L.P. As a result, each of the Reporting Persons may be deemed to share beneficial ownership of the Ordinary Shares directly reported herein, but each disclaims such beneficial ownership.

Number of Shares

The information contained on the cover pages to this Schedule 13D is incorporated by reference into this Item 5.

Transactions

During the past 60 days, Panacea Venture Healthcare Fund II, L.P. purchased 50,000 Ordinary Shares on September 30, 2025 in open market transactions on the Nasdaq Global Market for a weighted average price of $1.464 per Ordinary Share. Additionally, on November 24, 2025, Panacea Venture Healthcare Fund II, L.P. sold 2,000,000 Ordinary Shares for $3.00 per Ordinary Share.

Shareholders

None

Date of 5% Ownership

Not applicable.