On February 15, 2023, AI DMAB acquired 114,435 series B preference shares of Hemab ApS (the "Hemab ApS Series B Preferred Shares"), at a per share price of $305.85 in cash, for an aggregate purchase price of $34,999,944.75. AI DMAB funded this purchase using capital contributed from affiliated entities, which funded that capital using cash on hand. On October 23, 2025, AI DMAB acquired 57,217 series C preference shares of Hemab ApS (the "Hemab ApS Series C Preferred Shares"), at a per share price of $305.85 in cash, for an aggregate purchase price of $17,499,819.45. AI DMAB funded this purchase using capital contributed from affiliated entities, which funded that capital using cash on hand. On March 30, 2026, pursuant to a Share Contribution and Exchange Agreement by and among the Issuer, Hemab ApS and the holders party thereto, AI DMAB contributed its Hemab ApS Series B Preferred Shares and Hemab ApS Series C Preferred Shares to the Issuer in exchange for 114,435 shares of series B preferred stock of the Issuer, par value $0.0001 per share (the "Series B Preferred Stock"), and 57,217 shares of series C preferred stock of the Issuer, par value $0.0001 per share (the "Series C Preferred Stock"), respectively. No cash consideration was paid by AI DMAB in connection with such exchange. Upon the completion of the Issuer's initial public offering on May 4, 2026, and after giving effect to the Issuer's 22-for-one stock split of the Issuer's issued and outstanding Common Stock, AI DMAB's 114,435 shares of Series B Preferred Stock automatically converted into 2,517,570 shares of Common Stock and AI DMAB's 57,217 shares of Series C Preferred Stock automatically converted into 1,258,774 shares of Common Stock, in each case for no consideration. On May 4, 2026, AI DMAB purchased 1,100,000 shares of Common Stock in the Issuer's initial public offering at the public offering price of $18.00 per share. AI DMAB funded this purchase using capital contributed from affiliated entities, which funded that capital using cash on hand.

Lock-up Agreement In connection with the Issuer's initial public offering, on March 17, 2026, AI DMAB entered into a lock-up agreement (the "Lock-up Agreement") with Goldman Sachs & Co. LLC, Jefferies LLC and Evercore Group L.L.C., as representatives of the underwriters. Pursuant to the Lock-up Agreement, AI DMAB has agreed that it will not, directly or indirectly, offer, sell, contract to sell, pledge, grant any option, right or warrant to purchase, purchase any option or contract to sell, lend or otherwise transfer or dispose of any ordinary shares or preference shares of Hemab ApS, any shares of Common Stock, or any options or warrants to purchase any shares of Common Stock, or any securities convertible into, exchangeable for or that represent the right to receive shares of Common Stock, enter into any hedging, swap or other arrangement that transfers, in whole or in part, the economic consequences of ownership of Common Stock, make any demand for or exercise any right with respect to the registration of any such equity securities, or make any public announcement of an intention to do any of the foregoing for a period of 180 days following April 30, 2026, the date of the Issuer's prospectus filed pursuant to Rule 424(b)(4) with the SEC, without the prior written consent of Goldman Sachs & Co. LLC, Jefferies LLC and Evercore Group L.L.C., subject to certain exceptions. Goldman Sachs & Co. LLC, Jefferies LLC and Evercore Group L.L.C., on behalf of the underwriters, may release all or any portion of the securities subject to the Lock-up Agreement at any time and without notice before the termination of the 180-day period. The foregoing description of the Lock-up Agreement does not purport to be complete and is qualified in its entirety by reference to such, which is filed as an exhibit and incorporated herein by reference. Investors' Rights Agreement AI DMAB is party to an investors' rights agreement (the "Investors' Rights Agreement"), dated March 30, 2026, by and among the Issuer and certain of its stockholders named therein. Pursuant to the terms of the Investors' Rights Agreement, beginning 180 days after April 30, 2026, the effective date of the registration statement for the Issuer's initial public offering, holders who are party to the Investors' Rights Agreement and who collectively hold at least 30% of the then outstanding Registrable Securities (as defined therein) have the right to require the Issuer to file a registration statement on Form S-1 to register at least 25% of the then outstanding Registrable Securities, or a lesser percent if the anticipated aggregate offering price, net of selling expenses, would exceed $10 million, subject to customary terms and conditions. At any time the Issuer is eligible to use a Form S-3 registration statement, holders who are party to the Investors' Rights Agreement and who collectively hold at least 20% of the then outstanding Registrable Securities have the right to require the Issuer to file a registration statement on Form S-3 to register outstanding Registrable Securities of such holders having an anticipated aggregate offering price, net of selling expenses, of at least $5 million, subject to customary terms and conditions. Pursuant to the Investors' Rights Agreement, AI DMAB and its permitted transferees have customary piggyback registration rights, subject to customary terms and conditions. The foregoing description of the Investors' Rights Agreement does not purport to be complete and is qualified in its entirety by reference to such, which is filed as an exhibit and incorporated herein by reference. Joint Filing Agreement A Joint Filing Agreement, dated May 11, 2026, by and among the Reporting Persons has been executed by the Reporting Persons, a copy of which is attached hereto as Exhibit 99.4 and is incorporated herein by reference.

99.1 Annex A. 99.2 Lock-up Agreement, dated as of March 17, 2026, by and between AI DEN-MAB LLC, Goldman Sachs & Co. LLC, Jefferies LLC and Evercore L.L.C. as representatives of the several underwriters. 99.3 Investors' Rights Agreement, dated as of March 30, 2026, by and among Hemab Therapeutics Holdings, Inc. and certain of its stockholders (incorporated herein by reference to Exhibit 4.3 to the Issuer's Amendment No. 2 to the Form S-1 filed with the Securities and Exchange Commission on April 28, 2026). 99.4 Joint Filing Agreement, dated as of May 11, 2026. 99.5 Limited Power of Attorney.