13D Filings
HYPERION DEFI, INC.
HYPD
Amendment
Ownership

6.20%

Total Shares

354,291

Issuer CIK

1682639

CUSIP

30234E203

Event Date

Sep 11, 2025

Accepted

Sep 17, 2025, 03:36 PM

Reporting Persons (8)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Avenue Capital Management II, L.P.
Investment Adviser
6.20%354,291354,2910
Marc Lasry
Individual
6.20%354,29100
Avenue Venture Opportunities Partners II, LLC
Other
3.70%212,57500
Avenue Venture Opportunities Fund II, L.P.
Other
3.70%212,57500
GL Venture Opportunities Partners II, LLC
Other
3.70%212,57500
GL Venture Opportunities Partners, LLC
Other
2.50%141,71600
Avenue Venture Opportunities Partners, LLC
Other
2.50%141,71600
Avenue Venture Opportunities Fund, L.P.
Other
2.50%141,71600
Disclosure Items (7)

Security Title

COMMON STOCK, par value $0.0001 per share

Issuer Name

HYPERION DEFI, INC.

Issuer Address

23461 South Pointe Drive, Laguna Hills, CA, 92653

Filing Persons

The information set forth in Item 2(a) of the Schedule 13D is incorporated by reference. The Reporting Persons expressly disclaim status as a "group" for purposes of this Amendment. The agreement among the Reporting Persons to file jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Act is attached to the Schedule 13D as Exhibit 99.1 thereto. Other than those securities reported herein as being held directly by such Reporting Person, each Reporting Person disclaims beneficial ownership of all securities reported in this Amendment except to the extent of such Reporting Person's pecuniary interest, if any, therein.

Business Address

The information set forth in Item 2(b) of the Schedule 13D is incorporated by reference.

Principal Occupation

The information set forth in Item 2(c) of the Schedule 13D is incorporated by reference.

Convictions

The information set forth in Item 2(e) of the Schedule 13D is incorporated by reference.

Citizenship

The information set forth in Item 2(f) of the Schedule 13D is incorporated by reference.

The information set forth in Item 3 of the Schedule 13D is incorporated herein by reference.

(a) - (c) The information set forth in Item 4 of the Scheule 13D is incorporated by reference. This Amendment is being filed to report a change in Reporting Persons' beneficial ownership due to an increase in Issuer's outstanding shares of Common Stock.

Percentage of Class

See Items 7-11 and Item 13 of the cover page for each Reporting Person. The Reporting Persons are subject to a blocker that limits their beneficial ownership to 9.99% of the outstanding shares of Common Stock of the Issuer (the "Blocker"). The aggregate beneficial ownership by each Reporting Person gives effect to the Blocker and therefore excludes shares of common stock issuable upon exercise of the Warrants. The Blocker of 9.99% may be changed to up to 19.99% at the Reporting Persons' election upon at least 61 days' notice to the Issuer.

Number of Shares

See Items 7 through 11 of the cover page for each Reporting Person.

Transactions

Not applicable.

Shareholders

The information set for in Item 5(d) of the Schedule 13D is incorporated by reference.

Date of 5% Ownership

See Item 4.

The information set forth in Item 6 of the Schedule 13D is incorporated herein by reference.

Exhibit 99.1: Joint Filing Agreement by and among the Reporting Persons (filed as Exhibit 99.1 to Schedule 13D on May 15, 2025). https://www.sec.gov/Archives/edgar/data/1682639/000182912625003724/avenueventure_ex99-1.htm

HYPERION DEFI, INC. — Schedule 13D | 13D Filings