On December 19, 2024, the Issuer entered into a Subscription Agreement (the "2024 Subscription Agreement") with each of the Funds and certain other purchasers named therein (collectively, the "2024 PIPE Investors"). Pursuant to the 2024 Subscription Agreement, the Issuer agreed to sell to the Funds an aggregate of 8,333,000 pre-funded warrants (the "Pre-Funded Warrants") to acquire Common Stock at a purchase price of $2.3999 per share ( the "2024 PIPE Financing"). The Pre-Funded Warrants will have an exercise price of $0.0001 per share of Common Stock, be immediately exercisable, and remain exercisable until exercised in full. Neither Fund may exercise a Pre-Funded Warrant if such Fund, together with its affiliates, would beneficially own more than 19.99% of the number of shares of Common Stock outstanding immediately after giving effect to such exercise. Each Fund may decrease or, by providing at least 61 days' prior notice to the Issuer, increase such percentages not in excess of 19.99%. The closing of the 2024 PIPE Financing is expected to occur on a date that is no later than five business days from the date on which the Required Stockholder Approval (as defined in the 2024 Subscription Agreement) is obtained. The foregoing summaries of the 2024 Subscription Agreement and the Pre-Funded Warrants do not purport to be complete and are qualified in their entireties by reference to the 2024 Subscription Agreement and the form of Pre-Funded Warrant, which are included as Exhibit 99.6 and Exhibit 99.7, respectively, hereto and are incorporated herein by reference. At the closing of the 2024 PIPE Financing, in connection with the 2024 Subscription Agreement, the Issuer will enter into a 2025 Registration Rights Agreement (the "2025 Registration Rights Agreement") with the 2024 PIPE Investors. Pursuant to the 2025 Registration Rights Agreement, the Issuer is required to prepare and file a resale registration statement with the SEC on or prior to the later of (i) 30 calendar days following the closing of the 2024 PIPE Financing and (ii) five business days following the filing of the Issuer's audited financial statements for the year ended December 31, 2024. The Issuer will be required to use its commercially reasonable efforts to cause such registration statement to be declared effective by the SEC within 60 calendar days following the closing of the 2024 PIPE Financing (or within 90 calendar days following the closing of the 2024 PIPE Financing if the SEC reviews such registration statement), subject to acceleration under certain circumstances. The foregoing summary of the 2025 Registration Rights Agreement does not purport to be complete and is qualified in its entirety by reference to the form of 2025 Registration Rights Agreement, which is included as Exhibit 99.8 hereto and is incorporated herein by reference. In connection with the Issuer's execution of that certain Stock Purchase Agreement (the "Purchase Agreement") with KAKEN Investments Inc., a Delaware corporation ("Purchaser"), KAKEN Pharmaceutical Co., Ltd ("Guarantor"), and Aadi Subsidiary, Inc., a Delaware corporation and wholly owned subsidiary of the Issuer ("Private Aadi"), which provides that, on the terms and subject to the conditions set forth in the Purchase Agreement, the Purchaser will acquire 100% of the outstanding shares of capital stock of Private Aadi from the Issuer at the closing of the transactions contemplated thereby (the "Stock Purchase") for a purchase price of $100,000,000, subject to customary adjustments for Private Aadi's levels of cash, indebtedness, net working capital and transaction expenses as of the closing, each of the Funds entered into voting and support agreements with the Purchaser and the Issuer (the "Stockholder Support Agreements"). The Stockholder Support Agreements provide that, among other things, each of the Funds has agreed to vote or cause to be voted all of the shares of Common Stock beneficially owned by such Fund as of the record date of the meeting in favor of the Purchase Agreement, the Stock Purchase and the other transactions contemplated by the Purchase Agreement, as well as certain other transactions described in the Issuer's Current Report on Form 8-K filed with the SEC on December 20, 2024, at a special meeting of the Issuer's stockholders to be held in connection with, among other things, the Purchase Agreement, the Stock Purchase, the License Agreement (as defined and described in the Issuer's Current Report on Form 8-K filed with the SEC on December 20, 2024) and the 2024 PIPE Financing. The foregoing descriptions of the Purchase Agreement and Stockholder Support Agreements do not purport to be complete and are qualified in their entireties by reference to the Purchase Agreement and the form of the Stockholder Support Agreement, which are attached as Exhibit 2.1 to the Issuer's Current Report on Form 8-K filed with the SEC on December 20, 2024 and included as Exhibit 99.9 hereto, respectively, and are incorporated herein by reference.