13D Filings
Tenaya Therapeutics, Inc.
TNYA
Amendment
Ownership

25.40%

Total Shares

54,313,559

Issuer CIK

1858848

CUSIP

87990A106

Event Date

Feb 9, 2026

Accepted

Feb 12, 2026, 06:52 PM

Reporting Persons (8)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Tim Kutzkey
Individual
25.40%54,313,559054,313,559
Peter Svennilson
Individual
25.40%54,313,559054,313,559
The Column Group Opportunity III, LP
Partnership
23.10%49,313,559049,313,559
The Column Group Opportunity III GP, LP
Partnership
23.10%49,313,559049,313,559
TCG Opportunity III GP, LLC
Other
23.10%49,313,559049,313,559
The Column Group III GP, LP
Partnership
2.30%5,000,00005,000,000
The Column Group III-A, LP
Partnership
1.20%2,651,81702,651,817
The Column Group III, LP
Partnership
1.10%2,348,18302,348,183
Disclosure Items (7)

Security Title

Common Stock, par value $0.0001 per share

Issuer Name

Tenaya Therapeutics, Inc.

Issuer Address

171 Oyster Point Boulevard, South San Francisco, CA, 94080

Filing Persons

This Statement is being filed by The Column Group III, LP (TCG III LP), The Column Group III-A, LP (TCG III-A LP), The Column Group III GP, LP (TCG III GP LP), The Column Group Opportunity III, LP (TCG Opportunity III LP), The Column Group Opportunity III GP, LP (TCG Opportunity III GP LP), TCG Opportunity III GP, LLC (TCG Opportunity III GP LLC, together with TCG III LP, TCG III-A LP, TCG III GP LP, TCG Opportunity III LP, and TCG Opportunity III GP LP, the Reporting Entities), Tim Kutzkey and Peter Svennilson. The Reporting Entities, Tim Kutzkey and Peter Svennilson are collectively referred to as the Reporting Persons. Tim Kutzkey and Peter Svennilson have been added to this Statement as a Reporting Person as a result of the retirement of a managing partner of TCG III GP LP and a managing member of TCG Opportunity III GP LLC. The agreement among the Reporting Persons to file jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Act is attached hereto as Exhibit 1. Each Reporting Person disclaims beneficial ownership of all securities reported in this Statement except to the extent of such Reporting Person's pecuniary interest therein, other than those securities reported herein as being held directly by such Reporting Person.

Business Address

The address of the principal offices of each Reporting Person is 1 Letterman Drive, Building D, Suite M-900, San Francisco, CA 94129.

Principal Occupation

Each of TCG III LP, TCG III-A LP and TCG Opportunity III LP is a venture capital investment entity. TCG III GP LP is the general partner of each of TCG III LP and TCG III-A LP. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP. Dr. Kutzkey and Peter Svennilson are the managing partners of TCG III GP LP and the managing members of TCG Opportunity III GP LLC, and are each engaged through venture capital investment entities in acquiring, holding and disposing of interests in various companies for investment purposes.

Convictions

None of the Reporting Persons are, nor during the last five years have been, a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

Citizenship

Each of TCG III GP LP, TCG III LP, TCG III-A LP, TCG Opportunity III LP and TCG Opportunity III GP LP is a limited partnership organized under the laws of the State of Delaware. TCG Opportunity III GP LLC is a limited company organized under the laws of the State of Delaware. Dr. Kutzkey is a citizen of the United States of America. Mr. Svennilson is a citizen of Sweden.

Item 3 of the Original Schedule 13D is hereby amended by adding the following as the last paragraphs thereof: On February 10, 2026, TCG III LP sold an aggregate of 161,422 shares of the Issuer's Common Stock at a weighted-average price of $0.8161 per share and an aggregate sale price of approximately $0.13 million. On February 10, 2026, TCG III-A LP sold an aggregate of 182,295 shares of the Issuer's Common Stock at a weighted-average price of $0.8161 per share and an aggregate sale price of approximately $0.15 million. On February 11, 2026, TCG III LP sold an aggregate of 1,905,115 shares of the Issuer's Common Stock at a weighted-average price of $0.6808 per share and an aggregate sale price of approximately $1.3 million. On February 11, 2026, TCG III-A LP sold an aggregate of 2,151,458 shares of the Issuer's Common Stock at a weighted-average price of $0.6808 per share and an aggregate sale price of approximately $1.46 million.

The information set forth in Item 4 of the Original Schedule 13D is incorporated herein by reference.

Percentage of Class

See Items 7-11 of the cover pages of this Amendment No. 6.

Number of Shares

See Items 7-11 of the cover pages of this Amendment No. 6.

Transactions

Except as reported in this Statement, none of the Reporting Persons has affected any transactions in the Issuer's securities within the past 60 days.

Shareholders

Under certain circumstances set forth in the limited partnership agreements of each of TCG III LP, TCG III-A LP and TCG Opportunity III LP, the general partner and limited partners of TCG III LP, TCG III-A LP and TCG Opportunity III LP, as applicable, may be deemed to have the right to receive dividends from, or the proceeds from, the sale of shares of the Issuer owned by such entity of which they are a partner.

Date of 5% Ownership

Not applicable.

The information set forth in Item 6 of the Original Schedule 13D is incorporated herein by reference.

Exhibit 1: Joint Filing Agreement, dated February 12, 2026, by and among the Reporting Persons (filed herewith).