13D Filings
Nautilus Biotechnology, Inc.
NAUT
Amendment
Ownership

9.10%

Total Shares

11,634,211

Issuer CIK

1808805

Event Date

Jun 29, 2026

Accepted

Aug 14, 2026, 05:20 PM

Reporting Persons (4)
Joint Filing

This is a joint filing. The reported shares may overlap between reporting persons and should not be summed.

NameType% of ClassAggregateSole VotingShared Voting
Perceptive Advisors LLC
Investment Adviser
9.10%11,634,211011,634,211
Joseph Edelman
Individual
9.10%11,634,211011,634,211
Perceptive Life Sciences Master Fund, Ltd.
CO
9.10%11,468,351011,468,351
C2 Life Sciences LLC
CO
0.10%165,8600165,860
Disclosure Items (2)

Security Title

Common Stock, par value $0.0001 per share

Issuer Name

Nautilus Biotechnology, Inc.

Issuer Address

2701 Eastlake Avenue East, Seattle, WA, 98102

Percentage of Class

Item 5(a) of the Schedule 13D is hereby amended and restated as follows: The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference. The percentages set forth in row 13 are based on 127,255,223 shares of Common Stock outstanding as of July 24, 2026, as disclosed by the Issuer in its Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on July 28, 2026.

Number of Shares

The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference. Neither Perceptive Advisors LLC ( "Perceptive Advisors") nor Joseph Edelman ("Mr. Edelman") directly holds any Common Stock. Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund") directly holds 11,468,351 shares of Common Stock, and C2 Life Sciences LLC ("C2") directly holds 165,860 shares of Common Stock. Perceptive Advisors serves as the investment manager to the Master Fund and C2. Mr. Edelman is the managing member of Perceptive Advisors.

Nautilus Biotechnology, Inc. — Schedule 13D | 13D Filings